Pakistan must invest in both science and public education, and the Universities should expand synthetic biology programs
Prof Dr. Abdullah Arijo
Science is the most reliable path for human progress, offering evidence-based solutions to the challenges of health, environment, and society. When we cling to superstition or blind ritual, we risk ignoring the very tools that can improve our lives. By trusting in scientific inquiry, we embrace the qualities of curiosity, reason, and innovation that uplift communities and solve real problems. Science does not diminish spirituality; rather, it reminds us that the Creator endowed us with intellect to explore and understand the universe. Saying goodbye to superstition and welcoming science is not just a choice; it is a responsibility toward truth, dignity, and the betterment of humanity.
Science is no longer just about exploring outer space; it’s also about discovering the hidden universe inside our bodies. One of the most exciting breakthroughs is the engineering of gut bacteria. These tiny organisms live in our intestines, but they play a huge role in our health. They affect everything from immunity to mental well-being, and now scientists are learning how to reprogram them to fight disease. For countries like Pakistan, this could be life-changing.
READ: THE STATE OF BIOTECH INDUSTRY IN PAKISTAN
Synthetic biology allows researchers to design bacteria that can detect problems and even treat illnesses. For example:
- Special strains of E. coli have been created to release anti-inflammatory molecules in the gut, helping patients with Crohn’s disease or colitis.
- Other engineered microbes can break down harmful compounds, lower cholesterol, or produce essential vitamins.
Unlike regular medicines that spread through the whole body, these “living medicines” work directly in the gut. This means fewer side effects and better results. Clinical trials in the US and Europe are already showing promise, hinting that this future is nearer than we think.
Why Pakistan Must Not Ignore This
Pakistan struggles with two kinds of health problems:
- Infectious diseases are caused by poor sanitation, unsafe water, and antibiotic misuse.
- Lifestyle diseases like diabetes, heart problems, and inflammation, worsened by processed diets.
Gut health is connected to both. Engineered bacteria could be a low-cost solution, imagine probiotics designed for Pakistanis that boost immunity against waterborne diseases or reduce the effects of sugary diets. This could ease the burden on our already stretched healthcare system.
But here’s the challenge: Pakistan’s research and regulatory systems are not ready. Biotechnology is underfunded, and ethical rules for genetic engineering are still developing. Without investment, Pakistan risks falling behind while other nations move ahead.
The Global Race
Around the world, biotech companies are racing to develop “smart bacteria” that can sense disease and release treatments. Governments and investors are pouring money into this field.
For Pakistan, this is both a warning and an opportunity. If we don’t act, we’ll depend on costly imports. But if we invest in local expertise, Pakistan could become a regional leader in microbiome-based therapies. With our large population and diverse genetics, we’re in a unique position to test and develop innovations that could later be exported.
Challenges to Overcome
Of course, there are hurdles:
- Safety: Engineered bacteria must be tested carefully to avoid risks.
- Regulation: Governments worldwide are still figuring out how to monitor these therapies.
- Public trust: Many people are already skeptical about genetically modified crops. Convincing them to accept engineered microbes will require clear communication.
Pakistan must therefore invest in both science and public education. Universities should expand synthetic biology programs, and the media must help explain the benefits in simple terms. International collaborations can help, but local ownership is key.
A Call to Action
This is a moment of choice. Countries that prepare for the future of medicine will benefit; those that hesitate will fall behind. Pakistan has talented young scientists, but they need support and funding.
The government should:
- Build research centers for microbiome science.
- Encourage biotech startups.
- Integrate synthetic biology into national health strategies.
- Partner with agricultural universities to connect microbial research in crops and human health.
Above all, Pakistan must realize that health innovation is not optional, it’s essential.
Engineered gut bacteria may sound futuristic, but they are already moving from labs to hospitals. For Pakistan, the decision is clear: embrace this revolution and adapt it to local needs, or remain dependent on foreign technologies. These invisible microbes hold enormous potential. If used wisely, they could transform healthcare, reduce disease, and bring hope to millions. The time to act is now.
Read: Nourishing the Body Organ by Organ
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Abdullah Arijo is a professor and curriculum architect at Sindh Agriculture University, Tandojam, specializing in Parasitology, fisheries, aquaculture, zoology, and environmental sciences. He is also a civic advocate for climate resilience and sustainable development.
Professional & Academic.
An insightful piece by Prof. Dr. Abdullah Arijo. The potential for ‘living medicines’ and engineered gut bacteria to address Pakistan’s dual burden of infectious and lifestyle diseases is immense. However, as the author rightly points out, the lack of funding and a robust regulatory framework for biotechnology remains a significant bottleneck. It is high time our universities and policymakers prioritize synthetic biology to ensure we are creators of technology rather than just consumers of expensive imports.